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Cyclin E2 抗体 (pThr392)

This anti-Cyclin E2 antibody is a 兔 多克隆 antibody detecting Cyclin E2 in IF 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7225830
发货至: 中国

Quick Overview for Cyclin E2 抗体 (pThr392) (ABIN7225830)

抗原

See all Cyclin E2 (CCNE2) 抗体
Cyclin E2 (CCNE2)

适用

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  • 1
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人, 小鼠

宿主

  • 69
  • 1

克隆类型

  • 36
  • 34
多克隆

标记

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This Cyclin E2 antibody is un-conjugated

应用范围

  • 49
  • 33
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  • 4
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  • 1
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Immunofluorescence (IF), ELISA
  • 抗原表位

    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    pThr392

    原理

    Cyclin E2 (phospho Thr392) Polyclonal Antibody

    特异性

    Phospho-Cyclin E2 (T392) Polyclonal Antibody detects endogenous levels of Cyclin E2 protein only when phosphorylated at T392.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Cyclin E2 Phospho-Thr392

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Cyclin E2 (CCNE2)

    别名

    Cyclin E2

    背景

    Rabbit Anti-Cyclin E2 (phospho Thr392) Polyclonal Antibody,CCNE2, G1/S-specific cyclin-E2,The protein encoded by CCNE2 (cyclin E2)belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of CCNE2 peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.,G1

    基因ID

    9134

    UniProt

    O96020

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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