Cyclin E2 抗体 (pThr392)
Quick Overview for Cyclin E2 抗体 (pThr392) (ABIN7225830)
抗原
See all Cyclin E2 (CCNE2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr392
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原理
- Cyclin E2 (phospho Thr392) Polyclonal Antibody
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特异性
- Phospho-Cyclin E2 (T392) Polyclonal Antibody detects endogenous levels of Cyclin E2 protein only when phosphorylated at T392.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Cyclin E2 Phospho-Thr392
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cyclin E2 (CCNE2)
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别名
- Cyclin E2
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背景
- Rabbit Anti-Cyclin E2 (phospho Thr392) Polyclonal Antibody,CCNE2, G1/S-specific cyclin-E2,The protein encoded by CCNE2 (cyclin E2)belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of CCNE2 peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.,G1
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基因ID
- 9134
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UniProt
- O96020
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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