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Cyclin E2 抗体 (AA 355-404)

This 兔 多克隆 antibody specifically detects Cyclin E2 in WB, IHC, IF 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1532580
发货至: 中国
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Quick Overview for Cyclin E2 抗体 (AA 355-404) (ABIN1532580)

抗原

See all Cyclin E2 (CCNE2) 抗体
Cyclin E2 (CCNE2)

适用

  • 70
  • 34
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 70
  • 1
兔

克隆类型

  • 38
  • 33
多克隆

标记

  • 39
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
This Cyclin E2 antibody is un-conjugated

应用范围

  • 51
  • 31
  • 31
  • 22
  • 13
  • 12
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 355-404

    原理

    Cyclin E2 Antibody

    特异性

    Cyclin E2 Polyclonal Antibody detects endogenous levels of Cyclin E2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Cyclin E2. AA range:355-404

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Cyclin E2 (CCNE2)

    别名

    Cyclin E2

    背景

    Synonyms: CCNE2, G1/S-specific cyclin-E2

    Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008],

    Gene Name: CCNE2

    Protein Name: G1/S-specific cyclin-E2

    分子量

    46 kDa

    基因ID

    9134

    OMIM

    603775

    UniProt

    O96020

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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