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Cyclin D3 抗体 (pThr283)

This anti-Cyclin D3 antibody is a 兔 多克隆 antibody detecting Cyclin D3 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7225730
发货至: 中国

Quick Overview for Cyclin D3 抗体 (pThr283) (ABIN7225730)

抗原

See all Cyclin D3 (CCND3) 抗体
Cyclin D3 (CCND3)

适用

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人, 小鼠, 大鼠

宿主

  • 95
  • 15

克隆类型

  • 77
  • 33
多克隆

标记

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  • 6
  • 4
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  • 3
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  • 3
  • 3
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  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
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  • 1
  • 1
This Cyclin D3 antibody is un-conjugated

应用范围

  • 81
  • 33
  • 30
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  • 15
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  • 9
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 24
    • 16
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr283

    原理

    Cyclin D3 (phospho Thr283) Polyclonal Antibody

    特异性

    Phospho-Cyclin D3 (T283) Polyclonal Antibody detects endogenous levels of Cyclin D3 protein only when phosphorylated at T283.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Cyclin D3 Phospho-Thr283

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Cyclin D3 (CCND3)

    别名

    Cyclin D3

    背景

    Rabbit Anti-Cyclin D3 (phospho Thr283) Polyclonal Antibody,CCND3, G1/S-specific cyclin-D3,The protein encoded by CCND3 (cyclin D3) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for CCND3.,cyclin-D3

    分子量

    observerd band 32kDa

    基因ID

    896

    UniProt

    P30281

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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