CBP 抗体 (acLys1535)
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Quick Overview for CBP 抗体 (acLys1535) (ABIN7212580)
抗原
See all CBP (CREBBP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys1535
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原理
- CBP (Acetyl Lys1535) Polyclonal Antibody
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特异性
- Acetyl-CBP (K1535) Polyclonal Antibody detects endogenous levels of CBP protein only when acetylated at K1535.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human CBP around the acetylation site of K1535 at AA range: 1480-1550
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亚型
- IgG
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anti-CREB Binding Protein (CREBBP) (C-Term) antibody
KO Validated CREBBP 适用: 人 WB, IF, IP, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (C-Term) antibodyCREBBP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (AA 951-1050) antibodyCREBBP 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-CREB Binding Protein (CREBBP) (AA 144-193) antibodyCREBBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 兔, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (N-Term) antibodyCREBBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (C-Term) antibodyCREBBP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (AA 2217-2442) antibodyCREBBP 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) antibodyCREBBP 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) antibodyCREBBP 适用: 人 WB, IP, ICC, DB 宿主: 小鼠 Monoclonal CBP5I001 unconjugated
anti-CREB Binding Protein (CREBBP) (Ser262) antibodyCREBBP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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别名
- CBP
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背景
- Rabbit Anti-CBP (Acetyl Lys1535) Polyclonal Antibody,CREBBP, CBP, CREB-binding protein,CREBBP is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), CREBBP is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREB binding protein has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. CREB binding protein acetylates both histone and non-histone proteins. CREB binding protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in CREBBP cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving CREBBP have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms.,CREB-binding protein
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分子量
- observerd band 265kDa
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基因ID
- 1387
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UniProt
- Q92793
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途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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