CD35 抗体
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北京 101111
Quick Overview for CD35 抗体 (ABIN7226820)
抗原
See all CD35 (CR1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-CD35 Polyclonal Antibody
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特异性
- CD35 Polyclonal Antibody detects endogenous levels of CD35.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from CD35 at AA range: Internal
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亚型
- IgG
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anti-Complement Component Receptor 1 (CD35) (CR1) (AA 1780-2039) antibody
CR1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) antibodyCR1 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) antibodyCR1 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) (AA 420-550) antibodyCR1 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) antibodyCR1 适用: 人, Non-Human Primate FACS, IHC (p), IP, IHC (fro), ICC 宿主: 小鼠 Monoclonal E11 unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) antibody (FITC)CR1 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal E11 FITC
anti-Complement Component Receptor 1 (CD35) (CR1) antibodyCR1 适用: 人, Baboon, Cynomolgus, 猕猴 IHC, FACS, IF 宿主: 小鼠 Monoclonal E11 unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) antibodyCR1 适用: 人, Baboon, 猴 IHC, FACS, IF 宿主: 小鼠 Monoclonal CR1-802 unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) (AA 901-1095) antibodyCR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component Receptor 1 (CD35) (CR1) antibodyCR1 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 9A9 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
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别名
- CD35
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背景
- Complement component (3b/4b) receptor 1/2 (Knops blood group)CR1 (complement C3b/C4b receptor 1 (Knops blood group)) is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. CR1 encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in CR1 have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.
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分子量
- 220kD
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基因ID
- 1378
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UniProt
- P17927, Q2VPA4
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
抗原
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