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CSF1R 抗体 (pTyr723)

This 兔 多克隆 anti-CSF1R antibody specifically detects CSF1R in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7219724
发货至: 中国
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Quick Overview for CSF1R 抗体 (pTyr723) (ABIN7219724)

抗原

See all CSF1R 抗体
CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CSF1R antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pTyr723

    原理

    c-Fms (phospho Tyr723) Polyclonal Antibody

    特异性

    Phospho-c-Fms (Y723) Polyclonal Antibody detects endogenous levels of c-Fms protein only when phosphorylated at Y723.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human c-Fms Phospho-Tyr723

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

    别名

    c-Fms

    背景

    Rabbit Anti-c-Fms (phospho Tyr723) Polyclonal Antibody,CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD antigen CD115,Macrophage colony-stimulating factor 1 receptor encoded by CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.,Macrophage colony-stimulating factor 1 receptor

    分子量

    observerd band 108kDa

    基因ID

    1436

    UniProt

    P07333

    途径

    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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