CSF1R 抗体 (pTyr809)
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Quick Overview for CSF1R 抗体 (pTyr809) (ABIN7219718)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr809
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原理
- c-Fms (phospho Tyr809) Polyclonal Antibody
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特异性
- Phospho-c-Fms (Y809) Polyclonal Antibody detects endogenous levels of c-Fms protein only when phosphorylated at Y809.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human c-Fms Phospho-Tyr809
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- c-Fms
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背景
- Rabbit Anti-c-Fms (phospho Tyr809) Polyclonal Antibody,CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD antigen CD115,Macrophage colony-stimulating factor 1 receptor encoded by CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.,Macrophage colony-stimulating factor 1 receptor
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分子量
- observerd band 108kDa
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基因ID
- 1436
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UniProt
- P07333
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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