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Claudin 1 抗体 (AA 140-220)

This 兔 多克隆 anti-Claudin 1 antibody specifically detects Claudin 1 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7202631
发货至: 中国
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Quick Overview for Claudin 1 抗体 (AA 140-220) (ABIN7202631)

抗原

See all Claudin 1 (CLDN1) 抗体
Claudin 1 (CLDN1)

适用

  • 103
  • 56
  • 55
  • 22
  • 13
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 大鼠, 小鼠

宿主

  • 88
  • 18
  • 1

克隆类型

  • 87
  • 20
多克隆

标记

  • 52
  • 7
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
This Claudin 1 antibody is un-conjugated

应用范围

  • 79
  • 36
  • 27
  • 24
  • 18
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  • 15
  • 13
  • 10
  • 7
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 15
    • 10
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-220

    原理

    Claudin-1 Polyclonal Antibody

    特异性

    Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Claudin-1 at AA range: 140-220

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Claudin 1 (CLDN1)

    别名

    Claudin-1

    背景

    Rabbit Anti-Claudin-1 Polyclonal Antibody,CLDN1, CLD1, SEMP1, Claudin-1, Senescence-associated epithelial membrane protein,Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.,Claudin-1

    基因ID

    9076

    UniProt

    O95832

    途径

    Cell-Cell Junction Organization, Hepatitis C
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