NREP 抗体 (AA 30-110)
Quick Overview for NREP 抗体 (AA 30-110) (ABIN7225938)
抗原
See all NREP (C5orf13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- P311 Polyclonal Antibody
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特异性
- P311 Polyclonal Antibody detects endogenous levels of P311 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human P311 at AA range: 30-110
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))
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别名
- P311
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背景
- Rabbit Anti-P311 Polyclonal Antibody,NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311,P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability, the gene encoding P311 maps to human chromosome 5q22.,Neuronal regeneration-related protein
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基因ID
- 9315
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UniProt
- Q16612
抗原
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