NREP 抗体 (AA 13-62)
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北京 101111
Quick Overview for NREP 抗体 (AA 13-62) (ABIN1535102)
抗原
See all NREP (C5orf13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-62
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原理
- P311 Antibody
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特异性
- P311 Polyclonal Antibody detects endogenous levels of P311 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))
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别名
- C5orf13
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背景
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Synonyms: NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311
Background: P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability, the gene encoding P311 maps to human chromosome 5q22.
Gene Name: NREP
Protein Name: Neuronal regeneration-related protein
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分子量
- 7 kDa
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基因ID
- 9315
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OMIM
- 607332
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UniProt
- Q16612
抗原
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