Chordin 抗体 (AA 905-954)
Quick Overview for Chordin 抗体 (AA 905-954) (ABIN7227894)
抗原
See all Chordin (CHRD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 905-954
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原理
- Chordin Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of Chordin
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human Chordin protein at AA range: 905-954
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Chordin (CHRD)
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别名
- Chordin
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背景
- Rabbit Anti-Chordin Polyclonal Antibody,Chordin,CHRD encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that CHRD could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of CHRD results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined. CHRD (Chordin) is a Protein Coding gene. Diseases associated with CHRD include Cornelia De Lange Syndrome. Among its related pathways are Mesodermal Commitment Pathway and Signaling by BMP.,Chordin
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基因ID
- 8646
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UniProt
- Q9H2X0
抗原
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