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CDC25A 抗体 (pSer178)

This 兔 多克隆 anti-CDC25A antibody specifically detects CDC25A in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7226156
发货至: 中国
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Quick Overview for CDC25A 抗体 (pSer178) (ABIN7226156)

抗原

See all CDC25A 抗体
CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDC25A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer178

    原理

    Cdc25A (phospho Ser178) Polyclonal Antibody

    特异性

    Phospho-Cdc25A (S178) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S178.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Cdc25A Phospho-Ser178

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

    别名

    Cdc25A

    背景

    Rabbit Anti-Cdc25A (phospho Ser178) Polyclonal Antibody,CDC25A, M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A,CDC25A (cell division cycle 25A) is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.,M-phase inducer phosphatase 1

    分子量

    observerd band 59kDa

    基因ID

    993

    UniProt

    P30304

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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