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Caspase 2 抗体 (pSer157)

This 兔 多克隆 antibody specifically detects Caspase 2 in ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7225276
发货至: 中国
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北京 101111
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Quick Overview for Caspase 2 抗体 (pSer157) (ABIN7225276)

抗原

See all Caspase 2 (CASP2) 抗体
Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

适用

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宿主

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克隆类型

  • 91
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多克隆

标记

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This Caspase 2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer157

    原理

    Caspase-2 (phospho Ser157) Polyclonal Antibody

    特异性

    Phospho-Caspase-2 (S157) Polyclonal Antibody detects endogenous levels of Caspase-2 protein only when phosphorylated at S157.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Caspase-2 Phospho-Ser157

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

    别名

    Caspase-2

    背景

    Rabbit Anti-Caspase-2 (phospho Ser157) Polyclonal Antibody,CASP2, ICH1, NEDD2, Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1,CASP2 (caspase 2) encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CASP2.,Caspase-2

    基因ID

    835

    UniProt

    P42575

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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