CaMKIIalpha/delta 抗体 (pThr286)
Our Local Distributor
北京 101111
Quick Overview for CaMKIIalpha/delta 抗体 (pThr286) (ABIN7225194)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr286
-
原理
- Rabbit Anti-CaMKIIα/δ (phospho Thr286) Polyclonal Antibody
-
特异性
- Phospho-CaMKIIα/δ (T286) Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein only when phosphorylated at T286.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human CaMKIIalpha/delta Phospho-Thr286
-
亚型
- IgG
-
-
anti-CaMKIIalpha/delta (Lys542) antibody
适用: 人, 小鼠, 大鼠 IF, WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CaMKIIalpha/delta (pThr286) antibody适用: 人, 小鼠, 大鼠 IF, WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CaMKIIalpha/delta (Thr286) antibody适用: 人, 小鼠, 大鼠 IF, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- CaMKIIalpha/delta
-
背景
- CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2D, CAMKD, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase IIThe product of CAMK2A (calcium/calmodulin dependent protein kinase II alpha) belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for CAMK2A.
-
分子量
- 54kD
-
基因ID
- 815, 817
-
UniProt
- Q9UQM7, Q13557
抗原
-
