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CaMKIIalpha/delta 抗体 (Internal Region)

There is 1 publication for this product available. The 兔 多克隆 anti-CaMKIIalpha/delta antibody is suitable to detect CaMKIIalpha/delta in samples from 人, 小鼠 和 大鼠. It has been validated for IF, WB, IHC 和 ICC.
产品编号 ABIN6260427
发货至: 中国
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Quick Overview for CaMKIIalpha/delta 抗体 (Internal Region) (ABIN6260427)

抗原

CaMKIIalpha/delta

适用

  • 9
  • 9
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 9
This CaMKIIalpha/delta antibody is un-conjugated

应用范围

  • 9
  • 9
  • 8
  • 5
  • 4
  • 3
Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 抗原表位

    • 4
    • 1
    • 1
    • 1
    • 1
    Internal Region

    原理

    CaMKII alpha/delta Antibody

    特异性

    CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta

    预测反应

    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CaMK2 alpha/delta, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Cao, Xiao, Wang, Weng, Ding, Zhu, Lu: "Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).

  • 抗原

    CaMKIIalpha/delta

    别名

    CaMKII alpha/delta

    背景

    Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

    Gene: CAMK2A

    分子量

    50kDa

    基因ID

    815

    UniProt

    Q9UQM7
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