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CaMKIIalpha/delta 抗体 (pThr286)

The 兔 多克隆 anti-CaMKIIalpha/delta antibody is suitable to detect CaMKIIalpha/delta in samples from 人, 小鼠 和 大鼠. It has been validated for IF, WB, IHC 和 ICC.
产品编号 ABIN6256533
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CaMKIIalpha/delta 抗体 (pThr286) (ABIN6256533)

抗原

CaMKIIalpha/delta

适用

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  • 9
  • 9
  • 3
  • 2
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人, 小鼠, 大鼠

宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 9
This CaMKIIalpha/delta antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 抗原表位

    • 3
    • 2
    • 1
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    • 1
    pThr286

    原理

    Phospho-CaMKII alpha/delta (Thr286) Antibody

    特异性

    Phospho-CaMK2 (Thr286) Antibody detects endogenous levels of CaMK2 only when phosphorylated at Threonine 286

    预测反应

    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human CaMK2 alpha/delta around the phosphorylation site of Thr286.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CaMKIIalpha/delta

    别名

    CaMKII alpha/delta

    背景

    Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

    Gene: CAMK2A

    分子量

    50kDa

    基因ID

    815

    UniProt

    Q9UQM7
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