CaMKIIalpha/delta 抗体 (AA 256-305)
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Quick Overview for CaMKIIalpha/delta 抗体 (AA 256-305) (ABIN1532822)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 256-305
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原理
- CaMKIIα/δ Antibody
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特异性
- CaMKIIα/δ Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta. AA range:256-305
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CaMKIIalpha/delta (CaMK2 a/d) (Calcium/calmodulin-Dependent Protein Kinase II (CaMK2 a/d))
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别名
- CaMK2 alpha/delta
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背景
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Synonyms: CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2D, CAMKD, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II
Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
Gene Name: CAMK2A/CAMK2D
Protein Name: Calcium/calmodulin-dependent protein kinase type II subunit alpha/delta
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分子量
- 54 kDa
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基因ID
- 815, 817
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OMIM
- 114078
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UniProt
- Q9UQM7
抗原
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