APC 抗体 (pSer2054)
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Quick Overview for APC 抗体 (pSer2054) (ABIN7221552)
抗原
See all APC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer2054
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原理
- APC (phospho Ser2054) Polyclonal Antibody
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特异性
- Phospho-APC (S2054) Polyclonal Antibody detects endogenous levels of APC protein only when phosphorylated at S2054.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human APC Phospho-Ser2054
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亚型
- IgG
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anti-Adenomatous Polyposis Coli (APC) (AA 2636-2845) antibody
APC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2544-2843) antibodyAPC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2634-2842) antibodyAPC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (pSer2054) antibodyAPC 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (C-Term) antibodyAPC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2744-2843) antibodyAPC 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2751-2843) antibodyAPC 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (C-Term) antibodyAPC 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) antibodyAPC 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) antibodyAPC 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 5F2 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- APC (Adenomatous Polyposis Coli (APC))
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别名
- APC
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背景
- Rabbit Anti-APC (phospho Ser2054) Polyclonal Antibody,APC, DP2.5, Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 2.5,APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.,Adenomatous polyposis coli protein
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基因ID
- 324
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UniProt
- P25054
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途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
抗原
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