Actin 抗体
Our Local Distributor
北京 101111
Quick Overview for Actin 抗体 (ABIN7212046)
抗原
See all Actin (ACTA1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- α skeletal muscle actin Monoclonal Antibody
-
特异性
- The antibody detects endogenous α Skeletal Muscle Actin protein.
-
纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
-
免疫原
- Synthetic Peptide
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:5000-1:10000), IF (1:100-1:200), IHC-P (1:200), IP (1:200).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
-
别名
- alpha skeletal muscle actin
-
背景
- Mouse Anti-α skeletal muscle actin Monoclonal Antibody,ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1,Actin, alpha 1, skeletal muscle encoded by ACTA1 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in ACTA1 cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.,Actin alpha skeletal muscle
-
分子量
- observerd band 42kDa
-
基因ID
- 58
-
UniProt
- P68133
-
途径
- Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
抗原
-