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Actin 抗体

This 小鼠 单克隆 anti-Actin antibody specifically detects Actin in WB, IHC (p), IF 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7212046
发货至: 中国
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Quick Overview for Actin 抗体 (ABIN7212046)

抗原

See all Actin (ACTA1) 抗体
Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

适用

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人, 小鼠, 大鼠

宿主

  • 92
  • 31
小鼠

克隆类型

  • 74
  • 46
  • 1
单克隆

标记

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This Actin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    α skeletal muscle actin Monoclonal Antibody

    特异性

    The antibody detects endogenous α Skeletal Muscle Actin protein.

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Synthetic Peptide

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:5000-1:10000), IF (1:100-1:200), IHC-P (1:200), IP (1:200).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

    别名

    alpha skeletal muscle actin

    背景

    Mouse Anti-α skeletal muscle actin Monoclonal Antibody,ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1,Actin, alpha 1, skeletal muscle encoded by ACTA1 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in ACTA1 cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.,Actin alpha skeletal muscle

    分子量

    observerd band 42kDa

    基因ID

    58

    UniProt

    P68133

    途径

    Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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