NCKAP1 抗体 (AA 1001-1132) (Cy7)
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北京 101111
Quick Overview for NCKAP1 抗体 (AA 1001-1132) (Cy7) (ABIN715742)
抗原
See all NCKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1001-1132
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NCKAP1L
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亚型
- IgG
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anti-NCK Associated Protein 1 (NCKAP1) antibody
NCKAP1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) antibodyNCKAP1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) antibodyNCKAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) (AA 1-250) antibodyNCKAP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
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别名
- NCKAP1
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背景
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Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.
Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
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基因ID
- 10787
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UniProt
- P55160
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途径
- RTK signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
抗原
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