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NCKAP1 抗体

NCKAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7191586
发货至: 中国
  • 抗原 See all NCKAP1 抗体
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    适用
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    宿主
    • 46
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    克隆类型
    • 47
    多克隆
    标记
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    This NCKAP1 antibody is un-conjugated
    应用范围
    • 37
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    ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of Human NCKAP1
    亚型
    IgG
    Top Product
    Discover our top product NCKAP1 Primary Antibody
  • 应用备注
    ELISA:1:1000-1:2000, IHC:1:25-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    别名
    NCKAP1 (NCKAP1 产品)
    别名
    HEM2 antibody, NAP1 antibody, NAP125 antibody, p125Nap1 antibody, C79304 antibody, H19 antibody, Hem-2 antibody, Hem2 antibody, Nap1 antibody, mKIAA0587 antibody, mh19 antibody, NCK associated protein 1 antibody, NCK-associated protein 1 antibody, NCK-associated protein 1 L homeolog antibody, NCKAP1 antibody, Nckap1 antibody, nckap1.L antibody
    背景

    Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

    Aliases: FLJ11291 antibody, KIAA0587 antibody, Membrane associated protein HEM2 antibody, Membrane-associated protein HEM-2 antibody, MGC8981 antibody, NAP 1 antibody, NAP1 antibody, NAP125 antibody, NCK associated protein 1 antibody, NCK associated protein antibody, Nck-associated protein 1 antibody, Nckap1 antibody, NCKP1_HUMAN antibody, OTTHUMP00000163460 antibody, OTTHUMP00000163461 antibody, p125Nap1 antibody

    UniProt
    Q9Y2A7
    途径
    RTK signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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