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AKAP13 抗体 (AA 690-770)

This 兔 多克隆 anti-AKAP13 antibody specifically detects AKAP13 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7219274
发货至: 中国
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Quick Overview for AKAP13 抗体 (AA 690-770) (ABIN7219274)

抗原

See all AKAP13 抗体
AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))

适用

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宿主

  • 13
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克隆类型

  • 15
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多克隆

标记

  • 20
This AKAP13 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 4
    • 2
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    AA 690-770

    原理

    AKAP 13 Polyclonal Antibody

    特异性

    AKAP 13 Polyclonal Antibody detects endogenous levels of AKAP 13 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human AKAP 13 at AA range: 690-770

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))

    别名

    AKAP 13

    背景

    Rabbit Anti-AKAP 13 Polyclonal Antibody,AKAP13, BRX, HT31, LBC, A-kinase anchor protein 13, AKAP-13, AKAP-Lbc, Breast cancer nuclear receptor-binding auxiliary protein, Guanine nucleotide exchange factor Lbc, Human thyroid-anchoring protein 31, Lymphoid blast crisis oncogene, LBC,The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.,A-kinase anchor protein 13

    基因ID

    11214

    UniProt

    Q12802

    途径

    Neurotrophin Signaling Pathway
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