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Insulin Receptor 抗体 (AA 413-624)

This anti-Insulin Receptor antibody is a 小鼠 单克隆 antibody detecting Insulin Receptor in WB, ELISA, ICC 和 FACS. Suitable for 人, 小鼠 和 猴.
产品编号 ABIN7193923
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (AA 413-624) (ABIN7193923)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

  • 175
  • 91
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  • 8
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  • 4
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  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
人, 小鼠, 猴

宿主

  • 165
  • 30
  • 2
  • 1
小鼠

克隆类型

  • 151
  • 47
单克隆

标记

  • 128
  • 17
  • 15
  • 5
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  • 2
  • 2
  • 2
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  • 1
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  • 1
  • 1
  • 1
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  • 1
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This Insulin Receptor antibody is un-conjugated

应用范围

  • 145
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  • 2
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  • 1
  • 1
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

2A4H9
  • 抗原表位

    • 16
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    • 10
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
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    • 4
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 413-624

    原理

    CD220 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD220 (AA: 413-624) expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50 - 1/200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    Insulin Receptor (INSR)

    别名

    CD220

    背景

    This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

    分子量

    156 kDa

    基因ID

    3643

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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