FASL 抗体 (AA 103-281)
Quick Overview for FASL 抗体 (AA 103-281) (ABIN7193839)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 103-281
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原理
- CD178 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD178 (AA: 103-281) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- CD178
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背景
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This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
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分子量
- 31.5 kDa
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基因ID
- 356
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UniProt
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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