GANP 抗体 (AA 293-442)
Quick Overview for GANP 抗体 (AA 293-442) (ABIN7193448)
抗原
See all GANP (MCM3AP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 293-442
-
原理
- MCM3AP Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human MCM3AP (AA: 293-442) expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
- ELISA: 1/10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
-
别名
- MCM3AP
-
背景
-
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
-
分子量
- 218.4 kDa
-
基因ID
- 8888
-
UniProt
- O60318
-
途径
- Protein targeting to Nucleus
抗原
-