Parkin 抗体 (AA 1-144)
Quick Overview for Parkin 抗体 (AA 1-144) (ABIN7193428)
抗原
See all Parkin (PARK2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-144
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原理
- PRKN Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PRKN (AA: 1-144) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
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别名
- PRKN
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背景
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The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
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分子量
- 51.6 kDa
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UniProt
- O60260
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途径
- Autophagy, Ubiquitin Proteasome Pathway
抗原
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