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FADD 抗体 (AA 20-150)

FADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5A6A2 unconjugated
产品编号 ABIN7193411
发货至: 中国
  • 抗原 See all FADD 抗体
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    抗原表位
    • 16
    • 15
    • 13
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-150
    适用
    • 86
    • 51
    • 19
    • 18
    • 15
    宿主
    • 87
    • 18
    小鼠
    克隆类型
    • 81
    • 24
    单克隆
    标记
    • 65
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FADD antibody is un-conjugated
    应用范围
    • 88
    • 44
    • 30
    • 15
    • 15
    • 14
    • 11
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    FADD Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human FADD (AA: 20-150) expressed in E. Coli.
    克隆位点
    5A6A2
    亚型
    IgG1
    Top Product
    Discover our top product FADD Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    别名
    FADD (FADD 产品)
    背景

    The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

    分子量
    23.3 kDa
    基因ID
    8772
    UniProt
    Q13158
    途径
    Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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