IGF2R 抗体 (AA 160-311)
Quick Overview for IGF2R 抗体 (AA 160-311) (ABIN7193356)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 160-311
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原理
- CD222 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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别名
- CD222
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背景
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This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
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分子量
- 274 kDa
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基因ID
- 3482
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UniProt
- P11717
抗原
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