CCR2 抗体
Quick Overview for CCR2 抗体 (ABIN7193322)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CD192 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human CD192 expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
-
别名
- CD192
-
背景
-
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
-
分子量
- 41.9 kDa
-
途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-