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CCR2 抗体

CCR2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6B1 unconjugated
产品编号 ABIN7193322
发货至: 中国
  • 抗原 See all CCR2 抗体
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    适用
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    宿主
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    小鼠
    克隆类型
    • 77
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    单克隆
    标记
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    This CCR2 antibody is un-conjugated
    应用范围
    • 38
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    CD192 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CD192 expressed in E. Coli.
    克隆位点
    3B6B1
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    别名
    CD192 (CCR2 产品)
    背景

    The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.

    分子量
    41.9 kDa
    途径
    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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