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TNFRSF18 抗体 (AA 184-241)

TNFRSF18 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 6H8B9 unconjugated
产品编号 ABIN7193235
发货至: 中国
  • 抗原 See all TNFRSF18 抗体
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    抗原表位
    • 14
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 184-241
    适用
    • 56
    • 30
    • 2
    宿主
    • 37
    • 22
    • 22
    • 1
    小鼠
    克隆类型
    • 47
    • 33
    • 2
    单克隆
    标记
    • 54
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF18 antibody is un-conjugated
    应用范围
    • 41
    • 30
    • 25
    • 13
    • 12
    • 11
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA
    原理
    GITR Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. Coli.
    克隆位点
    6H8B9
    亚型
    IgG1
    Top Product
    Discover our top product TNFRSF18 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    别名
    GITR (TNFRSF18 产品)
    背景

    This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    分子量
    26 kDa
    基因ID
    8784
    UniProt
    Q9Y5U5
    途径
    Cancer Immune Checkpoints
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