TNFRSF18 抗体 (AA 184-241)
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- 抗原 See all TNFRSF18 抗体
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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抗原表位
- AA 184-241
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF18 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA
- 原理
- GITR Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. Coli.
- 克隆位点
- 6H8B9
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF18 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- 别名
- GITR (TNFRSF18 产品)
- 背景
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This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- 分子量
- 26 kDa
- 基因ID
- 8784
- UniProt
- Q9Y5U5
- 途径
- Cancer Immune Checkpoints
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