GTPase NRas 抗体
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北京 101111
Quick Overview for GTPase NRas 抗体 (ABIN7191712)
抗原
See all GTPase NRas (NRAS) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NRAS Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human NRAS
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GTPase NRas (NRAS)
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别名
- NRAS
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背景
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Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Aliases: ALPS4 antibody, AV095280 antibody, GTPase NRas antibody, HRAS1 antibody, N ras antibody, N ras protein part 4 antibody, Neuroblastoma RAS viral (v ras) oncogene homolog antibody, NRAS antibody, NRAS1 antibody, NS6 antibody, OTTHUMP00000013879 antibody, OTTMUSP00000023521 antibody, RASN_HUMAN antibody, Transforming protein N Ras antibody, Transforming protein N-Ras antibody, v ras neuroblastoma RAS viral oncogene homolog antibody
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UniProt
- P01111
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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