MED14 抗体
Quick Overview for MED14 抗体 (ABIN7191443)
抗原
See all MED14 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human MED14
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亚型
- IgG
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应用备注
- ELISA:1:2000-1:5000, IHC:1:25-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MED14 (Mediator Complex Subunit 14 (MED14))
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别名
- MED14
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背景
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Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Aliases: Activator-recruited cofactor 150 kDa component antibody, ARC150 antibody, Cofactor required for Sp1 transcriptional activation subunit 2 antibody, CRSP complex subunit 2 antibody, DRIP150 antibody, EXLM1 antibody, hRGR1 antibody, MED14 antibody, MED14_HUMAN antibody, Mediator complex subunit 14 antibody, Mediator of RNA polymerase II transcription subunit 14 antibody, RGR1 antibody, RGR1 homolog antibody, Thyroid hormone receptor-associated protein complex 170 kDa component antibody, Transcriptional coactivator CRSP150 antibody, Trap170 antibody, Vitamin D3 receptor-interacting protein complex 150 kDa component antibody
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UniProt
- O60244
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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