BNIP3L/NIX 抗体 (AA 51-150)
Quick Overview for BNIP3L/NIX 抗体 (AA 51-150) (ABIN714911)
抗原
See all BNIP3L/NIX (BNIP3L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BNIP3L
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亚型
- IgG
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 43-130) antibody
BNIP3L 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) antibodyBNIP3L 适用: 人, 小鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) antibodyBNIP3L 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 43-130) antibodyBNIP3L 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (Internal Region) antibodyBNIP3L 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H10B3 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 52-81) antibodyBNIP3L 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB19646 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 59-89), (Middle Region) antibodyBNIP3L 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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别名
- BNIP3L
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背景
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Synonyms: NIX, BNIP3a, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, NIP3-like protein X, NIP3L, BNIP3L, BNIP3H
Background: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
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基因ID
- 665
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UniProt
- O60238
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途径
- Autophagy
抗原
-
