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CTLA4 抗体 (C-Term)

The 兔 多克隆 anti-CTLA4 antibody (ABIN7189383) specifically detects CTLA4 in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7189383
发货至: 中国
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Quick Overview for CTLA4 抗体 (C-Term) (ABIN7189383)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    C-Term

    原理

    CTLA4 Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Synthetic peptide corresponding to residues near the C terminal of Human Cytotoxic T-lymphocyte protein 4

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

     pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CTLA4

    背景

    Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    Aliases: ALPS5 antibody, CD 152 antibody, CD antibody, CD152 antibody, CD152 antigen antibody, CD152 isoform antibody, Celiac disease 3 antibody, CELIAC3 antibody, CTLA 4 antibody, CTLA-4 antibody, CTLA4 antibody, CTLA4_HUMAN antibody, Cytotoxic T cell associated 4 antibody, Cytotoxic T lymphocyte antigen 4 antibody, Cytotoxic T lymphocyte associated 4 antibody, Cytotoxic T lymphocyte associated 4, soluble isoform, included antibody, Cytotoxic T lymphocyte associated antigen 4 antibody, Cytotoxic T lymphocyte associated antigen 4 short spliced form antibody, Cytotoxic T lymphocyte associated protein 4 antibody, Cytotoxic T lymphocyte associated serine esterase 4 antibody, Cytotoxic T lymphocyte protein 4 antibody, Cytotoxic T-lymphocyte protein 4 antibody, Cytotoxic T-lymphocyte-associated antigen 4 antibody, GRD4 antibody, GSE antibody, ICOS antibody, IDDM12 antibody, insulin-dependent diabetes mellitus 12 antibody, Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody, OTTHUMP00000216623 antibody

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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