ACVRL1 抗体
Quick Overview for ACVRL1 抗体 (ABIN7183058)
抗原
See all ACVRL1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human ACVL1.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
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别名
- ACVRL1
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背景
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Background: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
ten Dijke P., Oncogene 8:2879-2887(1993).
Attisano L., Cell 75:671-680(1993).
Berg J.N., Am. J. Hum. Genet. 61:60-67(1997).Aliases: Activin A receptor antibody, Activin A receptor type II like 1 antibody, Activin A receptor, type II like kinase 1 antibody, Activin receptor like kinase 1 antibody, Activin receptor-like kinase 1 antibody, ACVL1_HUMAN antibody, ACVRL1 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, Osler Rendu Weber syndrome 2 antibody, Serine/threonine protein kinase receptor R3 antibody, Serine/threonine-protein kinase receptor R3 antibody, SKR3 antibody, TGF B superfamily receptor type I antibody, TGF-B superfamily receptor type I antibody, TSR-I antibody, TSR1 antibody
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UniProt
- P37023
抗原
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