GRM8 抗体
Quick Overview for GRM8 抗体 (ABIN7181343)
抗原
See all GRM8 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from Human GluR8.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
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别名
- GRM8
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背景
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Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Patrick. M. Downey, J Biomol Screen, Dec 2005, 10: 841 - 848.
RJ Wenthold, J. Biol. Chem., Jan 1994, 269: 1332 - 1339.
Toshiaki Watanabe, Cancer Res., Oct 2006, 66: 9804 - 9808.
V. Bruno, J. Neurosci., Sep 2000, 20: 6413.Aliases: FLJ41058 antibody, GLUR8 antibody, Glutamate receptor metabotropic 8 antibody, GPRC1H antibody, GRM8 antibody, GRM8_HUMAN antibody, Metabotropic glutamate receptor 8 antibody, MGC126724 antibody, mGlu8 antibody, mGluR8 antibody
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UniProt
- O00222
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途径
- cAMP Metabolic Process, Synaptic Membrane
抗原
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