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GRM8 抗体

This 兔 多克隆 anti-GRM8 antibody specifically detects GRM8 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7181343
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRM8 抗体 (ABIN7181343)

抗原

See all GRM8 抗体
GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

适用

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宿主

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克隆类型

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多克隆

标记

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This GRM8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 原理

    GRM8 Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from Human GluR8.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

    别名

    GRM8

    背景

    Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

    Patrick. M. Downey, J Biomol Screen, Dec 2005, 10: 841 - 848.
    RJ Wenthold, J. Biol. Chem., Jan 1994, 269: 1332 - 1339.
    Toshiaki Watanabe, Cancer Res., Oct 2006, 66: 9804 - 9808.
    V. Bruno, J. Neurosci., Sep 2000, 20: 6413.

    Aliases: FLJ41058 antibody, GLUR8 antibody, Glutamate receptor metabotropic 8 antibody, GPRC1H antibody, GRM8 antibody, GRM8_HUMAN antibody, Metabotropic glutamate receptor 8 antibody, MGC126724 antibody, mGlu8 antibody, mGluR8 antibody

    UniProt

    O00222

    途径

    cAMP Metabolic Process, Synaptic Membrane
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