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WTAP 抗体 (C-Term)

This 兔 多克隆 anti-WTAP antibody specifically detects WTAP in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7180286
发货至: 中国
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Quick Overview for WTAP 抗体 (C-Term) (ABIN7180286)

抗原

See all WTAP 抗体
WTAP (Wilms Tumor 1 Associated Protein (WTAP))

适用

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宿主

  • 50
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克隆类型

  • 40
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多克隆

标记

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This WTAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    原理

    WTAP Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from C-terminal of Human WTAP.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    WTAP (Wilms Tumor 1 Associated Protein (WTAP))

    别名

    WTAP

    背景

    Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.

    Ortega A., J. Biol. Chem. 278:3040-3047(2003).
    Nagase T., DNA Res. 2:37-43(1995).
    Mungall A.J., Nature 425:805-811(2003).

    Aliases: DKFZp686F20131 antibody, Female-lethal(2)D homolog antibody, FL2D_HUMAN antibody, hFL(2)D antibody, KIAA0105 antibody, MGC3925 antibody, Mum2 antibody, OTTHUMP00000017522 antibody, OTTHUMP00000017523 antibody, PNAS 132 antibody, PNAS-132 antibody, PNAS132 antibody, Pre mRNA splicing regulator WTAP antibody, Pre-mRNA-splicing regulator WTAP antibody, Putative pre mRNA splicing regulator female lethal 2D homolog antibody, Putative pre mRNA splicing regulator female lethal(2D) antibody, Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody, putative pre-mRNA splicing regulator female-lethal(2D) antibody, Wilms tumor 1 associated protein antibody, Wilms tumor 1 associating protein antibody, Wilms tumor 1-associating protein antibody, Wilms' tumor 1 associating protein antibody, Wilms' tumour 1-associating protein antibody, WT1 associated protein antibody, WT1-associated protein antibody, WT1-associating protein antibody, wtap antibody

    UniProt

    Q15007
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