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PAK7 抗体 (C-Term)

This anti-PAK7 antibody is a 兔 多克隆 antibody detecting PAK7 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7180220
发货至: 中国

Quick Overview for PAK7 抗体 (C-Term) (ABIN7180220)

抗原

See all PAK7 抗体
PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

适用

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  • 1

宿主

  • 47

克隆类型

  • 47
多克隆

标记

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This PAK7 antibody is un-conjugated

应用范围

  • 31
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 8
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    C-Term

    交叉反应

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from C-terminal of Human PAK7.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000, IHC:1:50-1:100,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

    别名

    PAK5

    背景

    Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.

    Pandey A., Oncogene 21:3939-3948(2002).
    Nagase T., DNA Res. 6:337-345(1999).
    Deloukas P., Nature 414:865-871(2001).

    Aliases: EC 2.7.11.1 antibody, KIAA1264 antibody, MGC26232 antibody, p21 activated kinase 7 antibody, p21 protein (Cdc42/Rac)-activated kinase 7 antibody, p21(CDKN1A) activated kinase 7 antibody, p21-activated kinase 5 antibody, p21-activated kinase 7 antibody, PAK 5 antibody, PAK 7 antibody, PAK-5 antibody, PAK-7 antibody, PAK5 antibody, PAK7 antibody, PAK7_HUMAN antibody, Protein kinase PAK5 antibody, Serine/threonine protein kinase PAK 7 antibody, Serine/threonine-protein kinase PAK 7 antibody

    UniProt

    Q9P286
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