PAK7 抗体 (AA 128-157)
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北京 101111
Quick Overview for PAK7 抗体 (AA 128-157) (ABIN3028909)
抗原
See all PAK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 128-157
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原理
- Pak7 Antibody / Pak5
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交叉反应 （详细）
- Expected species reactivity: Rat
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 128-157 from the mouse protein was used as the immunogen for this Pak7 antibody.
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亚型
- Ig Fraction
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anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibody
PAK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1235 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157), (N-Term) antibodyPAK7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34659 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 26-55), (N-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 621-719) antibodyPAK7 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (Center) antibodyPAK7 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 183-198) antibodyPAK7 适用: 人 WB, IP, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the Pak7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Pak7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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别名
- Pak7
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背景
- Pak7, also called Pak5, is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions (By similarity). [UniProt]
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UniProt
- Q8C015
抗原
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