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PAK7 抗体 (N-Term)

PAK7 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043895
发货至: 中国
  • 抗原 See all PAK7 抗体
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-55, N-Term
    适用
    • 56
    • 16
    • 14
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 59
    克隆类型
    • 59
    多克隆
    标记
    • 24
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PAK7 antibody is un-conjugated
    应用范围
    • 42
    • 36
    • 32
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PAK 7(PAK7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    DPQEQKFTGL PQQWHSLLAD TANRPKPMVD
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PAK 7(PAK7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: p21 protein (Cdc42/Rac)-activated kinase 7
    Protein Name: Serine/threonine-protein kinase PAK 7
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human PAK5 (26-55aa DPQEQKFTGLPQQWHSLLADTANRPKPMVD), identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product PAK7 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    别名
    PAK7 (PAK7 产品)
    别名
    PAK5 antibody, pak5 antibody, 2900083L08Rik antibody, 6430627N20 antibody, Pak5 antibody, PAK-5 antibody, PAK-7 antibody, p21 (RAC1) activated kinase 5 antibody, p21 (RAC1) activated kinase 5 L homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 7 antibody, p21 (RAC1) activated kinase 7 antibody, PAK5 antibody, pak5.L antibody, Pak7 antibody
    背景
    Serine/threonine-protein kinase PAK 7, also known as PAK5, is an enzyme that in humans is encoded by the PAK7 gene. The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. And this kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. In addition, this kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

    Synonyms: EC 2.7.11.1 antibody|KIAA1264 antibody|MGC26232 antibody|p21 activated kinase 7 antibody|p21 protein (Cdc42/Rac)-activated kinase 7 antibody|p21(CDKN1A) activated kinase 7 antibody|p21-activated kinase 5 antibody|p21-activated kinase 7 antibody|PAK 5 antibody|PAK 7 antibody|PAK-5 antibody|PAK-7 antibody|PAK5 antibody|PAK7 antibody|PAK7_HUMAN antibody|Protein kinase PAK5 antibody|Serine/threonine protein kinase PAK 7 antibody|Serine/threonine-protein kinase PAK 7 antibody
    基因ID
    57144
    UniProt
    Q9P286
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