CAMK2B 抗体 (C-Term)
Quick Overview for CAMK2B 抗体 (C-Term) (ABIN7180135)
抗原
See all CAMK2B 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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                                            免疫原
- Synthesized peptide derived from C-terminal of Human CaMK2beta/γ,.
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                                            亚型
- IgG
 
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                                            应用备注
- WB:1:500-1:3000,
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
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                                            别名
- CAMK2G/CAMK2B
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                                            背景
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                        Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.Deloukas P., Nature 429:375-381(2004).Breen M.A., Biochem. Biophys. Res. Commun. 236:473-478(1997).Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997). Aliases: Calcium/calmodulin-dependent protein kinase type II gamma chain, EC 2.7.11.17, CaM-kinase II gamma chain, CaM kinase II subunit gamma, CaMK-II subunit gamma 
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                                            UniProt
- Q13555, Q13554
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                                            途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
 抗原
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