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BCAR1 抗体 (Tyr410)

This 兔 多克隆 anti-BCAR1 antibody specifically detects BCAR1 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7180057
发货至: 中国
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Quick Overview for BCAR1 抗体 (Tyr410) (ABIN7180057)

抗原

See all BCAR1 抗体
BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCAR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    Tyr410

    原理

    BCAR1 (Ab-410) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-T-A-V).

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

    别名

    BCAR1

    背景

    Background: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

    Katarzyna Modzelewska, J. Biol. Chem., Dec 2006, 281: 37527 - 37535.
    Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006, 291: H2857 - H2863.
    Sangkil Nam, Cancer Res., Oct 2005, 65: 9185 - 9189.
    Norikazu Yamana, Mol. Cell. Biol., Sep 2006, 26: 6844 - 6

    Aliases: BCAR 1 antibody, Bcar1 antibody, BCAR1_HUMAN antibody, Breast cancer anti estrogen resistance 1 antibody, Breast cancer anti estrogen resistance 1 protein antibody, Breast cancer anti-estrogen resistance protein 1 antibody, CAS antibody, Cas scaffolding protein family member 1 antibody, CAS1 antibody, Cass1 antibody, Crk associated substrate antibody, Crk associated substrate p130Cas antibody, CRK-associated substrate antibody, CRKAS antibody, FLJ12176 antibody, FLJ45059 antibody, p130cas antibody

    UniProt

    P56945

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
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