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NAMPT 抗体 (AA 231-491) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-NAMPT antibody (ABIN7178974) specifically detects NAMPT in ELISA. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7178974
发货至: 中国
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Quick Overview for NAMPT 抗体 (AA 231-491) (Biotin) (ABIN7178974)

抗原

See all NAMPT 抗体
NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This NAMPT antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 231-491

    原理

    Nampt Antibody, Biotin conjugated

    交叉反应

    大鼠

    纯化方法

    Antigen Affinity purified & Affinity purified

    纯度

    >95 %

    免疫原

    Recombinant Rat Nampt protein (231-491AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

    别名

    Nampt

    背景

    Background: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

    Aliases: Nampt antibody, Pbef1 antibody, Nicotinamide phosphoribosyltransferase antibody, NAmPRTase antibody, Nampt antibody, EC 2.4.2.12 antibody, Pre-B-cell colony-enhancing factor 1 homolog antibody, PBEF antibody, Visfatin antibody

    UniProt

    Q80Z29
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