PDK3 抗体 (AA 131-362) (HRP)
Quick Overview for PDK3 抗体 (AA 131-362) (HRP) (ABIN7176883)
抗原
See all PDK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-362
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交叉反应
- 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (131-362AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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别名
- Pdk3
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背景
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Background: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).
Aliases: Pdk3 antibody, [Pyruvate dehydrogenase antibody, acetyl-transferring)] kinase isozyme 3 antibody, mitochondrial antibody, EC 2.7.11.2 antibody, Pyruvate dehydrogenase kinase isoform 3 antibody
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UniProt
- Q922H2
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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