VPS11 抗体 (AA 692-941)
Quick Overview for VPS11 抗体 (AA 692-941) (ABIN7175282)
抗原
See all VPS11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 692-941
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Vacuolar protein sorting-associated protein 11 homolog protein (692-941AA)
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亚型
- IgG
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anti-Vacuolar Protein Sorting 11 Homolog (VPS11) antibody
VPS11 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Center) antibodyVPS11 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Internal Region) antibodyVerified VPS11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Internal Region) antibodyVPS11 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
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别名
- VPS11
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背景
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Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes (PubMed:21148287). Involved in the retrograde Shiga toxin transport (PubMed:23593995).
Aliases: END1 antibody, HGNC:14583 antibody, hVPS11 antibody, PEP5 antibody, PP3476 antibody, RING finger protein 108 antibody, RNF108 antibody, Vacuolar protein sorting 11 (yeast homolog) antibody, Vacuolar protein sorting 11 (yeast) antibody, Vacuolar protein sorting 11 homolog (S. cerevisiae) antibody, Vacuolar protein sorting 11 homolog antibody, Vacuolar protein sorting associated protein 11 homolog antibody, Vacuolar protein sorting protein 11 antibody, Vacuolar protein sorting-associated protein 11 homolog antibody, vps11 antibody, VPS11_HUMAN antibody
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UniProt
- Q9H270
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途径
- SARS-CoV-2 Protein Interactome
抗原
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