VPS11 抗体 (Internal Region)
-
- 抗原 See all VPS11 抗体
- VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This VPS11 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- VPS11 Antibody detects endogenous levels of total VPS11.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human VPS11, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product VPS11 Primary Antibody
-
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) antibody
VPS11 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Center) antibodyVPS11 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Internal Region) antibodyVerified VPS11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 692-941) antibodyVPS11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
- 别名
- VPS11 (VPS11 产品)
- 别名
- zgc:112329 antibody, ATVPS11 antibody, F5G3.7 antibody, F5G3_7 antibody, vacuolar protein sorting 11 antibody, DDBDRAFT_0204454 antibody, DDBDRAFT_0234135 antibody, DDB_0204454 antibody, DDB_0234135 antibody, end1 antibody, pep5 antibody, hvps11 antibody, rnf108 antibody, 1200011A11Rik antibody, END1 antibody, PEP5 antibody, RNF108 antibody, hVPS11 antibody, VPS11, CORVET/HOPS core subunit antibody, vacuolar protein sorting 11 antibody, vacuolar protein sorting protein 11 antibody, VPS11, CORVET/HOPS core subunit S homeolog antibody, Vacuolar peripheral membrane protein similar to S. cerevisiae PEP5 (YMR231W); C terminus is almost identical to nonallelic CaP19.1278 antibody, 7-fold repeat in clathrin and VPS proteins repeat-containing protein antibody, vacuolar protein sorting-associated protein 11 homolog antibody, VPS11 CORVET/HOPS core subunit antibody, VPS11 antibody, vps11 antibody, MCYG_02909 antibody, vps11.S antibody, LOC100632536 antibody, Vps11 antibody
- 背景
-
Description: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes (PubMed:21148287). Involved in the retrograde Shiga toxin transport (PubMed:23593995).
Gene: VPS11
- 分子量
- 108-112 kDa
- 基因ID
- 55823
- UniProt
- Q9H270
- 途径
- SARS-CoV-2 Protein Interactome
-
