RAD23A 抗体 (AA 2-201) (Biotin)
Quick Overview for RAD23A 抗体 (AA 2-201) (Biotin) (ABIN7175171)
抗原
See all RAD23A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-201
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human UV excision repair protein RAD23 homolog A protein (2-201AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RAD23A (RAD23 Homolog A (RAD23A))
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别名
- RAD23A
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背景
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Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to \\\'Lys-48\\\'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to \\\'Lys-63\\\'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.
Aliases: hHR 23A antibody, hHR23A antibody, HR23A antibody, MGC111083 antibody, RAD 23a antibody, RAD23 homolog A (S. cerevisiae) antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23A antibody, RD23A_HUMAN antibody, UV excision repair protein RAD23 antibody, UV excision repair protein RAD23 homolog A antibody
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UniProt
- P54725
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途径
- DNA Damage Repair
抗原
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