Tuberin 抗体 (AA 1396-1496)
Quick Overview for Tuberin 抗体 (AA 1396-1496) (ABIN7173643)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1396-1496
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Tuberin protein (1396-1496AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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别名
- TSC2
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背景
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Background: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.
Aliases: FLJ43106 antibody, LAM antibody, OTTHUMP00000158940 antibody, OTTHUMP00000198394 antibody, OTTHUMP00000198395 antibody, PPP1R160 antibody, Protein phosphatase 1, regulatory subunit 160 antibody, TSC complex subunit 2 antibody, tsc2 antibody, TSC2_HUMAN antibody, TSC4 antibody, TSC4 gene, formerly antibody, TSC4, formerly antibody, Tuberin antibody, Tuberous sclerosis 2 antibody, Tuberous sclerosis 2 protein antibody, Tuberous sclerosis 2 protein homolog antibody
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UniProt
- P49815
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途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
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