TSEN2 抗体 (AA 1-220)
Quick Overview for TSEN2 抗体 (AA 1-220) (ABIN7173540)
抗原
See all TSEN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-220
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human tRNA-splicing endonuclease subunit Sen2 protein (1-220AA)
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亚型
- IgG
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anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibody
TSEN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-465) antibodyTSEN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 395-444) antibodyTSEN2 适用: 人, 犬, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibodyTSEN2 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:200-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
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别名
- TSEN2
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背景
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Background: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5\\\'- and 3\\\'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2\\\',3\\\'-cyclic phosphate and 5\\\'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Isoform 1 probably carries the active site for 5\\\'-splice site cleavage. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3\\\'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3\\\'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. Isoform 2 is responsible for processing a yet unknown RNA substrate. The complex containing isoform 2 is not able to cleave pre-tRNAs properly, although it retains endonucleolytic activity.
Aliases: HsSen2 antibody, MGC2776 antibody, MGC4440 antibody, SEN2 antibody, SEN2_HUMAN antibody, SEN2L antibody, tRNA intron endonuclease Sen2 antibody, tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae) antibody, tRNA splicing endonuclease subunit Sen2 antibody, tRNA-intron endonuclease sen2 antibody, tRNA-splicing endonuclease subunit Sen2 antibody, TSEN 2 antibody, TSEN2 antibody
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UniProt
- Q8NCE0
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途径
- Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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