TARDBP 抗体 (AA 1-396)
Quick Overview for TARDBP 抗体 (AA 1-396) (ABIN7171509)
抗原
See all TARDBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-396
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human TAR DNA-binding protein 43 protein (1-396AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TARDBP
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背景
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Background: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3\\\'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3\\\' UTR.
Aliases: ALS10 antibody, OTTHUMP00000002171 antibody, OTTHUMP00000002172 antibody, OTTHUMP00000002173 antibody, TADBP_HUMAN antibody, TAR DNA binding protein 43 antibody, TAR DNA binding protein antibody, TAR DNA-binding protein 43 antibody, TARDBP antibody, TDP 43 antibody, TDP-43 antibody, TDP43 antibody
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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